Several workshops will be organized on Monday 9 in the afternoon. These workshops, which will include some tutorial aspects, will present novel equipments, methods and techniques and their use in the field of the ISP 2012 topics.
Advanced characterization of polymers, biopolymers and proteins by Dr. Carole Barbey (Instrumat-Malvern)
This workshop will present the different type of analysis used to characterize the physical properties of polymers, biopolymers and proteins. In particular, the measurement of molecular weight, molecular size, shape (conformation), electrical charge and affinity to bind to other molecules will be discussed. The principles of the various measurement techniques as well as the instrumentation required will be explained. As a new approach, the use of rheology to get additional information on protein formulations will be discussed.
Assessment of polyelectrolyte adsorption on solid surfaces by the streaming potential method by Dr. Thomas Luxbacher (Anton Paar GmbH)
The streaming potential method is commonly used to determine the zeta potential at the macroscopic solid/aqueous interface. Being extremely sensitive to the chemistry of the outermost solid surface, it is best suited to detect the adsorption of dissolved compounds onto the solid material. Technical and natural polyelectrolytes (such as proteins, polypeptides, enzymes, or polysaccharides) are highly charged polymers that affect the solid surface charge among adsorption. In this workshop you will learn about a powerful approach for the characterization of adsorption processes both under dynamic (adsorption kinetics) and steady-state conditions.
Correlated structural and quantitative analysis of multi-component systems by Anomalous Small-angle X-ray Scattering by Dr. GŁnter J. Goerigk (Helmholtz-Zentrum Berlin)
Synchrotron Radiation (SR) provides Small-Angle X-ray Scattering (SAXS) with major improvements, among others the photon flux, allowing the study of samples with only weak small-angle X-ray scattering like diluted chemical solutions. Additionally, the continuous energy spectrum of SR provides energy tunability in the vicinity of the K- and LIII-absorption edges of most of the elements giving access to an element specific structural and quantitative analysis. From this technique - known as Anomalous Small-Angle X-ray Scattering (ASAXS) – crucial chemical parameters like volume fractions and chemical concentrations can be obtained, which can be correlated to the structural properties.